illness
* buildup of metabolic waste
Persistent appetite loss deserves medical evaluation.
## 17. Nausea or Vomiting
Severely reduced kidney function can lead to nausea and vomiting.
These symptoms are common in many other illnesses, so they are most concerning when combined with other signs such as swelling, major changes in urination, or severe weakness.
## 18. Unexplained Weight Loss
Weight loss without trying can occur when appetite decreases or chronic illness affects nutrition.
Because unexplained weight loss has many potential causes, it should be medically assessed if it continues.
## 19. Shortness of Breath
Breathlessness can sometimes occur with kidney disease because of:
* anemia
* excess fluid
* associated heart problems
New or worsening shortness of breath should never be assumed to be kidney-related without proper evaluation.
## 20. Difficulty Sleeping
Sleep problems are common in people with chronic kidney disease.
Possible contributors include:
* itching
* restless legs
* cramps
* breathing problems
* discomfort
But insomnia itself is extremely
